ABSTRACT Bioskin is a new material produced by Acetobacter xylinum, Saccharomyces cerevisiae and Schyzosaccharomyces pombe in mixed culture on sucrose. The material has been revealed as hypoallergenic, antibiotic, antithermic and sedative. It is widely used for skin regeneration in the therapy of burns as well as in odontological surgery. Bioskin contains high amounts of D-glucosamine and N-acetyl-D-glucosamine. It does not produce ash after heating at 600°C and its combustion heat is similar to that of several current woods, such as pine, oak or maple. Bioskin has been used to immobilize algal cells, fungal spores and some bacteria in order to study some metabolic events. In addition, immobilization of several enzymes has been performed using bioskin as an inert matrix. Catalase was immobilized at pH 7.0 by ionic adsorption (aminosugars provide a net positive charge at neutral pH values) whereas several glycoproteins can be immobilized on bioskin by an affinity mechanism.
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