Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Cell & Molecular Biology   Volumes    Volume 11 
Role of low density neutrophils in human health and disease
Siavash Hassanpour, Flavia S. Lakschevitz, Noah Fine, Judah Glogauer, Elis Batistella, Farzeen Tanwir, Michael Glogauer
Pages: 1 - 17
Number of pages: 17
Trends in Cell & Molecular Biology
Volume 11 

Copyright © 2016 Research Trends. All rights reserved

Neutrophils, key cells of the innate immune system, are still regarded as a relatively homogeneous cell population with minimal discernible phenotypic and functional diversity. Amongst the reasons for this misconception is the fact that neutrophils are still largely defined by their morphology. In comparison, other immune cells, such as lymphocytes and macrophages, are now well known to form distinct subsets that differ morphologically and phenotypically. Recently, there has been a paradigm shift in the understanding of neutrophil diversity. The identification of low density neutrophils (LDN), a subpopulation of neutrophils initially described in patients with rheumatic diseases, has begun a new era in neutrophil biology research. The aim of this review paper is to describe LDNs in the context of a number of pathological and physiological conditions including systemic lupus erythematosus (SLE), cancer, human immunodeficiency virus (HIV), sepsis, asthma, and pregnancy. Within the context of each condition, this paper will discuss briefly the techniques used to isolate and characterize LDNs while focusing on the phenotype, function, proposed origin and physiological development of LDNs in each condition.
Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms