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Current Trends in Endocrinology   Volumes    Volume 11 
Early detection of glucose dysregulation (GD) in patients with β-thalassemia major: Review of current diagnostic criteria and the ICET-A survey
Vincenzo de Sanctis, Ashraf Soliman, Ploutarchos Tzoulis, Shahina Daar, Antonis Kattamis, Polyxeni Delaporta, Mohamed A. Yassin, Mehran Karimi, Duran Canatan, Soad Al Jaouni, Maria Concetta Galati, Giuseppe Raiola, Giuseppe Messina, Saveria Campisi, Forough Saki, Dulani Kottahachchi, Valeria Kaleva, Kristina Petrova, Atanas Banchev, Yurdanur Kilinc, Christos Kattamis
Pages: 1 - 11
Number of pages: 11
Current Trends in Endocrinology
Volume 11 

Copyright © 2020 Research Trends. All rights reserved

The high prevalence of diabetes mellitus (DM) in subjects with β-thalassemia major (TM) requires targeted screening so that glucose dysregulation (GD) can be detected as early as possible. The determination of the optimal method for identifying patients at risk for progression from impaired fasting glucose (IFG) and impaired glucose tolerance (IGT) to diabetes mellitus (DM) is challenging and remains an area of considerable research interest. This report reviews the current diagnostic criteria for prediabetes and DM, highlights controversies and new diagnostic challenges, and reports the preliminary data of a survey promoted by the International Network of Clinicians for Endocrinopathies in Thalassemia and Adolescent Medicine (ICET-A) on the criteria used for the diagnosis and monitoring of GD by 15 centers providing care to patients with TM.
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