Accumulation of copper in liver, spleen, kidney, muscle, testis and brain tissues of M.musculus var. albinus was studied after daily injection of copper subcutaneously and orally at concentrations of 0, 2, 6, 10 and 14 mg/kg wet weight over 21 days period. Tissue accumulations of copper were determined using Atomic Absorption Spectrophotometer techniques.
Copper accumulation in the tissues increased with increasing concentrations of copper injected. Accumulation was highest in liver and lowest in muscle tissues. At a given concentration accumulation was higher when copper was injected subcutaneously then injected orally.
Buy this Article