Approximately 5% to 10% of all skin cancers occur in the eyelid; basal cell carcinoma (BCC) is the most frequent (90%). A 38-year-old man, affected by Gorlin-Goltz syndrome, presented with a BCC in the left lateral canthus area. Photodynamic therapy (PDT) with methyl-aminolaevulinate (MAL) after Frost suture was performed without anaestesia. Very good results were obtained with rapid healing and without side effects. There was no evidence of scar formation and no signs of recurrence at 5 years follow-up. Many therapeutic methods have been suggested for basal cell carcinoma of the eyelids. We consider photodynamic treatment of eyelid skin malignancies to be of great interest; it represents an interesting new procedure for their management especially when surgical intervention is not tolerated, and for patients with many lesions as in Gorlin Goltz Syndrome.
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