Chronic antiorthostatic therapy (CAT) creates reduced gravity effects and chronically applied periodic blood boost to the brain (BBB) which help the brain to recover the capabilities lost due to a disease or trauma. We hypothesized that CAT can treat Alzheimer’s disease. We therefore studied the potential clinical benefits of CAT to Alzheimer’s patients. Studies were performed on sixty male and female patients aging 74.5 ± 11.0 years with mild to moderate Alzheimer’s. They were divided into two groups. The 1^st group that was treated with CAT and the prescribed medication served as the experimental group and the 2^nd group that was treated with the prescribed medication alone served as the control group. They were studied during the pre-experimental period of two plus years and the experimental period of eight plus years. The Alzheimer’s patients of the 1^st group showed positive effects compared to the patients of the 2^nd group and the pre-experimental period symptoms. The patients of the 1^st group with mild Alzheimer’s were free from the symptoms and the patients of moderate Alzheimer’s were free from most of the symptoms. On the other hand the 2^nd group of patients with mild to moderate Alzheimer’s were not free from symptoms compared to the patients of the 1^st group with mild and moderate Alzheimer’s disease. The current study provides evidence for treatment of Alzheimer’s disease using CAT, suggesting a potential clinical therapy for Alzheimer’s patients with CAT, through chronically-applied periodic BBB and reduced Earth gravity effects.