Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Current Topics in Virology   Volumes    Volume 14 
Cervical tissue-based organ culture as a model to study HIV-1 transmission
Phalguni Gupta, Anwesha Sanyal
Pages: 39 - 46
Number of pages: 8
Current Topics in Virology
Volume 14 

Copyright © 2017 Research Trends. All rights reserved

Sexual transmission via vaginal intercourse accounts for majority of human immunodeficiency virus type 1 (HIV-1) in women. The mechanism by which HIV-1 traverses the tightly bound tissue structure of cervical/vaginal epithelium, especially when vaginal/cervical epithelial cells do not express HIV-1 receptor or co-receptors is still unknown. With the restrictions on studying these mechanisms in humans and the substantial anatomical differences between human and non-human primates, investigators have used cervical tissue-derived organ culture models that closely mimic the human in vivo environment to study HIV-1 transmission. This report reviews our current knowledge of various cervical tissue-derived organ cultures and their application in studying HIV-1 transmission and microbicide development.
Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms