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Current Topics in Toxicology   Volumes    Volume 14 
Combined superwarfarin poisoning with extremely high levels of bromadiolone
Mariángeles Marossero, Florencia Falguera, María Graciela Quevedo, María Macarena Parot Varela, Nancy Mónica Olivera, Adriana Silvia Ridolfi, Valentina Olmos
Pages: 89 - 93
Number of pages: 5
Current Topics in Toxicology
Volume 14 

Copyright © 2018 Research Trends. All rights reserved

Long-acting anticoagulant rodenticides are responsible for many human poisonings around the world. This communication reports a self-poisoning of a 40 year-old woman with an anticoagulant rodenticide with more than fifteen times the maximum allowed concentration for commercial rodenticides. Bromadiolone and brodifacoum were identified in the patient’s serum. Serum bromadiolone levels exceeded 30 µg/L. The high concentration reached by bromadiolone, the fact that two superwarfarins were found in the patient’s serum, as well as the good prognosis and evolution of the case represent the highlights of this communication. The rapid onset of vitamin K1 therapy, together with the potential presence of resistance-related factors, could have led to the favorable outcome of the case.
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