ABSTRACT 2-(Naphthalen-1-yl)acetyl isothiocyanate 3 is used as a building block in the synthesis of, quinazoline, benzothiazole, 1,2,4-triazole, 1,2,4,5-tetrazine and thiourea derivatives. All the synthesized compounds bear a lipophilic methyl naphthalene moiety (a hydrocarbon moiety) in order to enhance their antibacterial and antifungal activities. The antimicrobial activity of some of the synthesized compounds was tested.
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