Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
ID:
Password:
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

Agents/Distributors
 Regional Subscription Agents/Distributors
 
Current Topics in Biochemical Research   Volumes    Volume 16 
Abstract
Long noncoding RNAs and their expanding roles in cancer
Edward J. Richards, Jin Q. Cheng
Pages: 81 - 95
Number of pages: 15
Current Topics in Biochemical Research
Volume 16 

Copyright © 2014 Research Trends. All rights reserved

ABSTRACT
 
Protein-coding genes only account for about 2% of the total human genome. Recent technologies (e.g., tiling arrays and RNA-sequencing) have revealed that about 70% of the human genome is transcribed into noncoding RNAs. Long noncoding RNAs (lncRNAs), which comprise of a class of RNA molecules greater than 200 nucleotides in length, have been emerging as critical players in a broad range of cellular processes. More recently, a dozen of human lncRNAs have been implicated in driving cancer development through their oncogenic or tumor suppressive functions. This review aims to broadly define the functions and mechanisms of lncRNAs in the context of cancer, as well as discuss their potential future applications in the clinic.
View Full Article  


 
search


E-Commerce
Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Login
Search Products
Browse in Alphabetical Order : Journals
Series/Books
Browse by Subject Classification : Journals
Series/Books

Miscellaneous
Ordering Information Ordering Information
Downloadable forms Downloadable Forms