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Current Topics in Virology   Volumes    Volume 18 
Abstract
SARS-CoV-2 morphology, genome, life cycle and our bodies’ immune response: a review
Ilyes Zatla, Lamia Boublenza, Hafida Hassaine
Pages: 15 - 24
Number of pages: 10
Current Topics in Virology
Volume 18 

Copyright © 2021 Research Trends. All rights reserved

ABSTRACT
 
A novel coronavirus strain has been testing the capabilities of our modern world and suffocating health care systems, while bringing together scientist`s researches and governmental powers, to fight off its robust viral disease. A new zoonotic pathogenic member of the human coronaviruses, that was first documented in Wuhan, China, has crossed the species barrier to infect humans and caused an outbreak of viral pneumonia. In this brief review, we’ll discuss the virology of SARS-CoV-2, the virus that causes COVID-19, covering the general structure of the virus, its genetics and its process of replication. SARS-CoV-2 gets into the cell through the recognition of the angiotensin-converting enzyme 2 (ACE2) receptors by the spike glycoprotein, with the aid of the priming protein transmembrane serine protease 2 (TMPRSS2), which is important for its activation, and replicates as a result of a complex process that involves RNA synthesis, proofreading and capping.
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