The results of a study on processing of titanium-, tungsten- and boron-containing mineral raw materials using NH₄HF₂, (NH₄)₂SO₄ and a mixture of these reagents are presented. It was shown that when heated, the solid-phase interaction of the mineral raw material with the indicated reagents proceeds, while at temperatures up to 200 °C, the components of the mineral raw material are fluorinated with the formation of simple and complex fluorides. A further increase in temperature leads to the formation of ammonium hydrosulfate (NH₄HSO₄), which, upon interaction with the formed fluorides leads to their conversion into soluble double sulfates. It was shown that a mixture of NH₄HF₂ and (NH₄)₂SO₄ can be considered as a new promising reagent for the processing of certain types of mineral raw materials. The ways of extracting the components of mineral raw materials in the form of marketable products are shown.