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Current Trends in Immunology   Volumes    Volume 20 
Retrospective study of myasthenia gravis in a sample of patients at the University Hospital of Rabat, Morocco
Majda Samih, A. O. T. Ahami
Pages: 43 - 52
Number of pages: 10
Current Trends in Immunology
Volume 20 

Copyright © 2019 Research Trends. All rights reserved

The purpose of this study is to highlight a chronic neuromuscular disease characterized by a rapid weakening and exhaustion of voluntary muscles: ‘Myasthenia gravis’ (MG). It is an autoimmune disease that belongs to a broad class of disorders characterized by the irregular response of immune cells that create auto-reactive antibodies that target its own cells and tissues. This disease presents in different forms in different individuals. Myasthenia is almost three times more common among women than men. This report concerns 117 clinically confirmed myasthenic and electromyographic patients who had been hospitalized in the neurology department of a specialized hospital in Rabat, Morocco. Patient records were archived by the doctors of the Department of Neurology. Several parameters have been studied clinically in this sampling. This research included 31 men and 86 women, 26% and 74% of the total sample respectively. This study also describes the associated diseases for both sexes, as well as the diagnostic methods and the used treatments. Myasthenia gravis is a condition that occurs at any age, with two peaks of frequency; the first between the second and fourth decades of life, with a strong female predominance. The second peak is observed from age 50 with a clear male tendency. The responsible factors are still poorly understood.
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