Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Current Trends in Immunology   Volumes    Volume 20 
The immunological chimera mother/baby persists and functionally reverses after birth: immune monitoring of the milk and its role in active immunotherapy
Li-En Hsieh, Negar Benhamfar, Lars Bode, Alessandra Franco
Pages: 71 - 78
Number of pages: 8
Current Trends in Immunology
Volume 20 

Copyright © 2019 Research Trends. All rights reserved

Very little is known about the timing for the T cell development in infants and young children that, in sharp contrast with mice, lasts until puberty. Our work suggests that immune regulation is the main efferent arm of the innate and adaptive immunity in pediatric age. Maternal immune cells are transferred with the milk to the baby indicating that the immunological microchimera plays an important protective role in the immune homeostasis of infants. Here we review the immune cells of the mother/offspring microchimera in the uterus/placenta interface during pregnancy and the immune cells transferred to the baby by maternal milk after birth. We also discuss possible outcomes that may lead to pathology with a new light on T cell alloreactivity.
View Full Article  


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms