Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Photochemistry & Photobiology   Volumes    Volume 21 
Effect of dipeptide derivative Schiff-base Zn(II) complexes on lysozyme molecules damaged by means of IR-FEL irradiation
Yuika Onami, Takayasu Kawasaki, Tomoyuki Haraguchi, Koichi Tsukiyama, Dohyun Moon, Yasutaka Kitahama, Takuya Hosokai, Hiroyuki Matsuzaki, Hiroshi Sakiyama, Takashiro Akitsu
Pages: 15 - 26
Number of pages: 12
Trends in Photochemistry & Photobiology
Volume 21 

Copyright © 2022 Research Trends. All rights reserved

An infrared free-electron laser can decompose aggregated proteins (including metal complexes) via the excitation of their vibrational bands. In this study, using the results of previous studies on human serum albumin, we prepared hybrid materials of chicken egg white lysozyme protein with the same Schiff-base Zn(II) complexes by incorporating glycylglycine dipeptide derivative moieties. The analysis of secondary structures after irradiation indicated that the inclusion of the Zn(II) complexes into lysozyme induced structural changes in lysozyme, resulting in a more fragile structure than that of the original lysozyme; this is the second reported example of the enhancing effect of a metal complex on protein molecules damaged by IR-FEL irradiation. Their docking features via weak intermolecular interactions were also investigated using fluorescence spectra (quenching, temperature dependence, and decay lifetime) with the aid of computational simulation of docking.
View Full Article  


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms