Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Photochemistry & Photobiology   Volumes    Volume 21 
Twenty years’ experience of extracorporeal photopheresis in low body weight paediatric patients
Joris Bonnet, Alexandre Armand, Victoria Grèze, Emmanuelle Rochette, Nadège Rouel, Pascale Halle, Etienne Merlin, Justyna Kanold
Pages: 27 - 39
Number of pages: 13
Trends in Photochemistry & Photobiology
Volume 21 

Copyright © 2022 Research Trends. All rights reserved

In children, extracorporeal photopheresis (ECP) procedures are often a real challenge as many variables must be considered for safe management of paediatric apheresis. For small children, available information is even more anecdotal. We describe our experience of ECP treatment in children weighing up to 25 kg. From January 1996 to December 2015 a total of 1245 ECP collections were performed in paediatric patients. Among these, 327 ECP collections concerned 19 paediatric patients under 25 kg classified into three body weight groups for data analysis. Cells were collected using a COBE® Spectra or Spectra Optia separator. Venous access was chosen on a case-by-case basis. Over the years increasingly smaller patients were accepted with similarly smaller volumes collected. We found a significant difference concerning the choice of vascular access in the different groups and patients weighing less than 15 kg had the lowest rates of lymphocyte collection efficiency. No major adverse events were observed, including in children weighing less than 15 kg. Over a 20-year period, ECP has been a safe treatment even in small children, with good tolerance and very few adverse effects. However, its clinical use is sometimes limited by logistical issues such as venous access failure, poor medical condition, severe cytopenia, non-compliance, or long distance from collection centre.
Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms