Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Current Topics in Biochemical Research   Volumes    Volume 22 
Exploring the role of vitamin D receptor signaling in skeletal muscle: Lessons learned from genetically modified mice
Akira Wagatsuma, Masayuki Arakawa
Pages: 17 - 23
Number of pages: 7
Current Topics in Biochemical Research
Volume 22 

Copyright © 2021 Research Trends. All rights reserved

Vitamin D exerts its biological actions via the vitamin D receptor (VDR). VDR is expressed in many tissues albeit at variable expression. The localization of VDR in myofibers has been confirmed by immunohistochemistry. VDR signaling has been recognized as a potential regulator of myogenesis. Data linking VDR mutations to various muscle phenotypes have been gradually increasing. Genetic animal models accelerate our understanding of the molecular mechanisms by which VDR signaling regulates normal muscle homeostasis. These insights will be valuable in bridging molecular mechanisms and therapeutic strategies for age-related muscle wasting such as sarcopenia. Here, we outline the studies using genetic-modified mice that reveal the role of VDR signaling in muscle structure and function.
Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms