Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
ID:
Password:
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

Agents/Distributors
 Regional Subscription Agents/Distributors
 
Current Topics in Pharmacology   Volumes    Volume 24 
Abstract
Use of nutraceuticals in peripheral compressive neuropathies: current clinical evidence and future perspectives
Luca Dalle Carbonare, Enrica Baraldi
Pages: 119 - 136
Number of pages: 18
Current Topics in Pharmacology
Volume 24 

Copyright © 2020 Research Trends. All rights reserved

ABSTRACT
 
Peripheral compressive neuropathies (PCNs) include several chronic syndromes, such as cervicobrachialgia, lumbalgia, lumbosciatalgia and carpal tunnel syndrome. All of these conditions are characterised by pain and sensorial symptoms, which include analgesia, paraesthesia and allodynia. In the absence of a surgical indication or in case of delayed intervention, the conservative treatment is based on both analgesic and anti-inflammatory drugs, with potential risks of side effects, particularly in elderly, and physical therapy. Thus, the search for effective and safe substances represents an unmet medical need. In this review, we examine the rationale for the development of a new multicomponent nutraceutical and its potential use in the treatment of PCNs. A multicomponent nutraceutical that contains acetyl-L-carnitine (ALC), palmitoylethanolamide (PEA), Boswellia serrata (BS), vitamin B6 and vitamin E has been recently developed (Kalanit®, Chiesi Farmaceutici S.p.A., Italy). We examine the possible mechanism of action of all components and the available clinical evidence in their clinical use in peripheral neuropathies. As a result of our search, it can be postulated that the new multicomponent nutracetical may be an effective and well tolerated supplement in the management of PCNs, either as a single agent or in combination with conventional pharmacological and/or physical therapies. 
View Full Article  


 
search


E-Commerce
Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Login
Search Products
Browse in Alphabetical Order : Journals
Series/Books
Browse by Subject Classification : Journals
Series/Books

Miscellaneous
Ordering Information Ordering Information
Downloadable forms Downloadable Forms