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Current Topics in Pharmacology   Volumes    Volume 25 
Evaluation of quality of life and awareness of adverse drug reaction reporting among patients with dermatological adverse drug reactions
S. Goutam, P. Das, S. Jena, S. Mohapatra, C. Kaushik, S. Mohapatra
Pages: 85 - 90
Number of pages: 6
Current Topics in Pharmacology
Volume 25 

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Adverse drug reactions (ADRs) are a common cause of morbidity and mortality worldwide and are only to rise in the future due to the increasing trend in self-medication, polypharmacy, marketing of new drugs and fixed combinations and increase in geriatric population. The dermatological ADRs not only out-number all other ADRs but are also unique in being significantly disturbing and adversely affecting the quality of life. So the current study focuses on these aspects along with awareness of ADR reporting. This is a cross-sectional study conducted on 74 participants within the study period and all the dermatological ADRs were recorded on the suspected ADR reporting form of PvPI (Pharmacovigilance Programme of India). ADRs were assessed for causality, severity and preventability using appropriate scales. The quality of life was assessed by using Dermatology Life Quality Index (DLQI) and the awareness of ADR reporting using appropriate questionnaire. The mean age of the study was 36.4 years and males were more commonly affected. Drug hypersensitivity reaction was the most common finding followed by fixed drug eruption. Antibiotics and non-steroidal anti-inflammatory drugs (NSAIDs) were the most common medication associated. Maximum ADRs were mild in nature, possibly due to the drug and were not preventable. The quality of life was extremely severely affected in maximum participants. Though the severe cases of dermatological ADRs are less, the quality of life hampered is far greater. The awareness of ADR among common people is quiet low.
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