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Current Topics in Pharmacology   Volumes    Volume 3 
Abstract
Mechanistic aspects in the hepatic uptake of long chain free fatty acids, bile acids and non-bile acids cholephilic organic anions
Adriana Mónica Torres
Pages: 137 - 144
Number of pages: 8
Current Topics in Pharmacology
Volume 3 

Copyright © 1997 Research Trends. All rights reserved

ABSTRACT
 
Many organic and inorganic compounds cross the hepatic cell plasma membrane in both directions. The liver plays an important role in the clearance of different compounds from the blood stream. Consequently, much attention has been paid to the physicochemical and energetic mechanisms governing hepatic uptake. This review will focus mainly on the role of plasma membrane carriers accounting for liver uptake of long chain free fatty acids, bile acids and non-bile acids cholephilic organic anions. The different transporters identified by the classical and the molecular approach are described.
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