Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Current Topics in Biochemical Research   Volumes    Volume 3 
Carbohydrate-binding protein galectin-3: its role in metastasis, angiogenesis and apoptosis
Pratima Nangia-Makker, Sara Baccarini, Avraham Raz
Pages: 229 - 236
Number of pages: 8
Current Topics in Biochemical Research
Volume 3 

Copyright © 2000 Research Trends. All rights reserved


Galectin-3 is a member of a protein family defined by having at least one characteristic carbohydrate-recognition domain (CRD) with an affinity for β-galactosides and sharing certain conserved sequence elements. Galectins are soluble 14-36 kDa proteins and 11 have been identified in mammals, 3 in birds, and many in other species including frogs, fish, worms, a marine sponge, and a fungus. Galectin specificity at a molecular level is determined by recognition of a distinct glyco-conjugate, which triggers diverse biological reactions. The same galectin species seems to participate in development, differentiation, morphogenesis, immunity, apoptosis, metastasis of malignant cells, angiogenesis etc. Therefore, a complete understanding of the physiological functions of galectins still has not been achieved. Following is an overview of the studies performed in our and other laboratories on the role of galectin-3 in metastasis, angiogenesis and apoptosis.

Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms