Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Developmental Biology   Volumes    Volume 3 
Control of cell differentiation and programmed cell death during digit development
René Fernando Abarca-Buis, Alberto Ríos-Flores, Rodrigo Cuervo, Marcia Bustamante, Jesús Chimal-Monroy
Pages: 71 - 81
Number of pages: 11
Trends in Developmental Biology
Volume 3 

Copyright © 2008 Research Trends. All rights reserved

The morphological diversity of the vertebrate limb is the result of finely tuned responses to signals that emanate from organizer centers controlling the three embryonic axes that shape the limb throughout processes such as apoptosis, differential growth and cell differentiation. When the autopod begins to form, an undifferentiated group of cells subjacent to the Apical Ectodermic Ridge (AER) respond to chondrogenic or pro-apoptotic signals. In this review, we briefly describe some experiments that identified the principal signals responsible for promoting cartilage differentiation and cell death. As the interdigit has a chondrogenic potential, we discuss the existing balance between chondrogenic and apoptotic signals that setup the digit-interdigit pattern for establishing the undifferentiated autopodial cells destiny.
Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms