Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Cancer Research   Volumes    Volume 3 
Radioimmunotherapy in adjuvant settings to treat small metastatic lesions: experimental results in a liver metastasis model and a peritoneal dissemination model of colon cancer in mice
Seigo Kinuya
Pages: 75 - 87
Number of pages: 13
Trends in Cancer Research
Volume 3 

Copyright © 2007 Research Trends. All rights reserved

Radioimmunotherapy (RIT) employing radiolabeled monoclonal antibodies (MAb) against tumors has been extensively tested for more than two decades. Although results of RIT in patients with malignant lymphoma are encouraging, the results in other types of tumors are less favorable in bulky disease. In contrast, several reports suggest the role of RIT as an adjuvant treatment of cancer. However, in treating small lesions, especially when cancer cells are spread in the peritoneal cavity but do not produce tumors, loss of decay energy outside of small lesions occurs because of millimeter path length of β particle. In contrast, previous works have indicated that RIT employing β emitters effectively treated lesions smaller than their path length. In this article, our experimental results in animal models of colon cancer cells are summarized to support feasibility of adjuvant RIT in minimal disease.
Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms