Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Cancer Research   Volumes    Volume 4 
Preparation and investigation of antitumor drug Arglabin-loaded human serum albumin (HSA) nanoparticles
L. Zhaparova, Y. Tazhbayev, M. Burkeev, C. Adekenov, K. Ulbrich, J. Kreuter
Pages: 43 - 47
Number of pages: 5
Trends in Cancer Research
Volume 4 

Copyright © 2008 Research Trends. All rights reserved

In the present study the possibility of the binding of the antitumor drug arglabin to human serum albumin (HSA) nanoparticles by adsorption was investigated. The particle size did not change after drug adsorption and was about 160 nm. Drug binding as well as the influence of arglabin on the physico-chemical characteristics of the nanoparticles was analysed. More than 60% of the initially added arglabin could be bound to the HSA nanoparticles at low drug concentrations.  At higher concentrations a plateau was reached with a minimum concentration of 39% of the added amount of arglabin yielding a loading of 13.5% compared to the HSA nanoparticle mass.
Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms