Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Comparative Biochemistry & Physiology   Volumes    Volume 4 
Fatty acid-binding proteins. Chronological description and discussion of hypotheses involving their molecular evolution
Jose A. Santomé, Santiago M. Di Pietro, Brian M. Cavagnari, Osvaldo L. Córdoba, Esteban C. Dell’Angelica
Pages: 23 - 38
Number of pages: 16
Trends in Comparative Biochemistry & Physiology
Volume 4 

Copyright © 1998 Research Trends. All rights reserved

Cytosolic fatty acid-binding proteins (FABPs) were first described in 1972 and, during several years, most of the studies involved only mammals. These proteins are present in nearly all mammal tissues and a high degree of primary structure similarity has been found between FABPs of the same tissue in different species. They were classified into several types - such as liver, heart, intestinal, adipocyte, myelin, ileal and epidermal - on account of the first tissue they were isolated from. However, this tissue specificity does not hold true for fish. We have reviewed the chief publications on molecular evolution of these proteins and comment herein on the amino acid sequence of over 60 FABPs and those evolutionary trees proposed so far. Our contribution concerning the evolution of the different types is presented in a chronological relation to previous papers by other authors and also to those appearing later on. We have isolated over 15 FABPs from different animals (chimera fish, elasmobranchs, bone fish, amphibians and mammals) and partially or fully determined their primary structure. Our results are discussed in relation to the current hypotheses.
Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms