Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
ID:
Password:
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

Agents/Distributors
 Regional Subscription Agents/Distributors
 
Current Topics in Virology   Volumes    Volume 5 
Abstract
Impact of genetic engineering on plum pox virus disease
M. Ravelonandro
Pages: 63 - 69
Number of pages: 7
Current Topics in Virology
Volume 5 

Copyright © 2006 Research Trends. All rights reserved

ABSTRACT

With the paucity of natural resistance sources to sharka virus, substantial progress has been  achieved by pathologists in understanding the  plum pox virus (PPV) genome. The alternative approach that we developed to create resistant plants is a case study in the interactions between  PPV and it host. The endemic presence of PPV in Central, Balkan, and Mediterranean Europe, with the distinct environments of each area, and the multiplicity of isolates provides a particularly useful field for the assessment of virus resistant germplasm. Under these conditions the genetically engineered PPV resistant plum clone C-5 expressed its resistance phenotype over a long period. Among the basic criterion for genetically modified plant (GMP) acceptance is the preservation of the environment. Studies of emerging PPV variants have received particular research attention. Virus resistance in C5 was triggered by the silencing machinery involving the PPV transgene which involves the production of small interfering RNAs (siRNA) which are constitutively activated. While lesser information about the consequent molecular interactions between PPV and the virus transgene can be depicted from susceptible clones, the investigations we conducted allowed to demonstrate the safe use of transgenic woody perennial plums that will grow for more than 10 years in field. Our studies revealed the molecular stability of PPV and subsequently no any emerging PPV have derived from virus/transgene interactions.

Buy this Article


 
search


E-Commerce
Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Login
Search Products
Browse in Alphabetical Order : Journals
Series/Books
Browse by Subject Classification : Journals
Series/Books

Miscellaneous
Ordering Information Ordering Information
Downloadable forms Downloadable Forms