The incidence of esophageal adenocarcinoma (EAC) is on the rise. Barrett’s esophagus (BE) is considered to be a precursor in the development of EAC and thus it is important to diagnose this condition. Risk of BE associated EAC is particularly high in older white males and those with high grade dysplasia. Screening for BE is routinely performed in those with long standing gastro-esophageal reflux symptoms. Although the true cost-benefit of cancer surveillance in Barrett’s esophagus is still not fully understood, periodic surveillance based on the presence or absence of dysplasia is recommended as per current guidelines. Several treatment modalities are available for treatment of BE with dysplasia ranging from photodynamic therapy and radio-frequency ablation to esophagectomy and their selection should be individualized based on local expertise and patient preferences.
Buy this Article