Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
ID:
Password:
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

Agents/Distributors
 Regional Subscription Agents/Distributors
 
Current Topics in Steroid Research   Volumes    Volume 6 
Abstract
Functionalization of steroid skeleton via transition metal complexes catalyzed homogeneous reactions
Szilárd Tőrös
Pages: 1 - 20
Number of pages: 20
Current Topics in Steroid Research
Volume 6 

Copyright © 2009 Research Trends. All rights reserved

ABSTRACT
 
This review comprises some recent results on the transition metal catalyzed homogeneous carbonylation reactions dealing with the synthesis of practically important compounds. Selected examples are given for both the functionalization of various biologically important skeletons and their build-up from appropriate building blocks via carbonylation reactions by using carbon monoxide. The short review illustrates, that hydroformylation has also gained importance in the functionalization of steroidal compounds providing formyl functionality for further ‘build-up’ of the skeleton. Saturated and unsaturated esters can be obtained in hydroalkoxy-carbonylation reaction, respectively. Using enol triflates or iodo-alkenes as substrates various conjugated unsaturated esters and amides can be synthesised in good yields in the presence of alcohol or amine nucleophiles. The intramolecular alkoxycarbonylation and aminocarbonylation reactions became a widely used tool for the synthesis of lactones and lactames, respectively. The homogeneous catalytic reactions provide efficient ways for the synthesis of compounds of practical importance.
Buy this Article


 
search


E-Commerce
Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Login
Search Products
Browse in Alphabetical Order : Journals
Series/Books
Browse by Subject Classification : Journals
Series/Books

Miscellaneous
Ordering Information Ordering Information
Downloadable forms Downloadable Forms