ABSTRACT This review comprises some recent results on the transition metal catalyzed homogeneous carbonylation reactions dealing with the synthesis of practically important compounds. Selected examples are given for both the functionalization of various biologically important skeletons and their build-up from appropriate building blocks via carbonylation reactions by using carbon monoxide. The short review illustrates, that hydroformylation has also gained importance in the functionalization of steroidal compounds providing formyl functionality for further ‘build-up’ of the skeleton. Saturated and unsaturated esters can be obtained in hydroalkoxy-carbonylation reaction, respectively. Using enol triflates or iodo-alkenes as substrates various conjugated unsaturated esters and amides can be synthesised in good yields in the presence of alcohol or amine nucleophiles. The intramolecular alkoxycarbonylation and aminocarbonylation reactions became a widely used tool for the synthesis of lactones and lactames, respectively. The homogeneous catalytic reactions provide efficient ways for the synthesis of compounds of practical importance.
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