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Current Topics in Biotechnology   Volumes    Volume 7 
Abstract
Bioconversion of acetophenones by marine fungi isolated from marine algae Bostrychia radicans and Sargassum sp.
Ana Maria Mouad, Mariana Provedel Martins, Stelamar Romminger, Mirna Helena Regali Seleghim, Ana Ligia Leandrini de Oliveira, Hosana Maria Debonsi, Nair Sumie Yokoya, Mutue Toyota Fujii, Michel Rodrigo Zambrano Passarini, Rafaella Costa Bonugli-Santos, Lara Durães Sette, André Luiz Meleiro Porto
Pages: 13 - 19
Number of pages: 7
Current Topics in Biotechnology
Volume 7 

Copyright © 2012 Research Trends. All rights reserved

ABSTRACT
 
The bioconversion of acetophenone derivatives 1-6 was investigated using whole cells of marine fungi Botryosphaeria sp. Br-09, Eutypella sp. Br-023, Hydropisphaera sp. Br-27 and Xylaria sp. Br-61 isolated from the red alga Bostrychia radicans and Arthopyrenia sp. SGPY-41, Penicillium sp. SMA2-8, Pestalotiopsis sp. SMA2-C isolated from brown alga Sargassum sp. Asymmetric reduction produced the enantiopure (R)- or (S)-alcohols 7-12 with high enantiomeric excess (>99 % ee). This study describes the first investigation with marine-derived fungi recovered from algae for biocatalytic reduction. The fungus Botryosphaeria sp. Br-09 showed excellent reductions for ortho-acetophenone derivatives 1-6.
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