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Trends in Heterocyclic Chemistry   Volumes    Volume 8 
Abstract
The mechanisms of sulfonyl transfer in strained cyclic sulfonamides
J. Matthew Wood, Michael I. Page
Pages: 19 - 34
Number of pages: 16
Trends in Heterocyclic Chemistry
Volume 8 

Copyright © 2002 Research Trends. All rights reserved

ABSTRACT

The reactivity and reaction mechanisms of sulfonyl compounds are reviewed. Particular attention is paid to the reactions of 1,2-thiazetidine-1,1-dioxides, β-sultams, a new class of reactive sulfonamides. Aspects of the hydrolysis reactions of these compounds, including their reactive intermediates, is discussed and their potential as novel enzyme inhibitors described.

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