Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Developmental Biology   Volumes    Volume 8 
Immunoreactivity of Mel1a-like melatonin receptor and NRH: Quinone reductase enzyme (QR2) in testudine whole embryo and in developing whole retinas
Renata Nunes Silva, Lucia de Fatima Sobral Sampaio
Pages: 39 - 46
Number of pages: 8
Trends in Developmental Biology
Volume 8 

Copyright © 2014 Research Trends. All rights reserved

Melatonin, the molecule signaling darkness, is possibly related with the development of the vertebrates. In developing chick retinas, Mel1a-like melatonin receptor (Mel1a) has been observed at embryonic day (E) 8 and after. NRH: Quinone reductase enzyme (QR2) is a detoxifying enzyme that binds melatonin analogs in developing chick retinas. In this study, whole mounted E21 embryos and whole retinas of the E21 embryos and juvenile Kinosternon scorpioides (JKs) were submitted to immunoassays to investigate the presence of Mel1a and QR2. Texas Red immunofluorescence for QR2 and Mel1a was diffusely localized in whole retinas of the E21 embryos and of the JKs. In E21 whole embryos, Texas Red immunofluorescence for Mel1a was localized in forelimb, hindlimb, peripheral carapace and tail. Mel1a immune signals were also present in choroid fissure of the optic cup, and in a region that corresponds to frontonasal process, mandibular process and maxillary process. QR2 was present in maxillary process region, in lens/iris, forelimb, hindlimb and tail. The results suggest that melatonin must have functions in testudine development by binding Mel1a and QR2.
View Full Article  


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms