ABSTRACT Synthetic studies are reviewed on phospha sugars, sugar analogs having a phosphorus atom in the hemiacetal ring, e.g., analogs of D-glucose, D-mannose, D-galactose, L-fucose, D-fructose. By converting them into the corresponding per-o-acetyl derivatives, structures and conformations of phospha sugars have been established by 1H-NMR spectral analyses. Various methods and their stereoselectivity of the C-P bond introduction onto various types of 6-nitro-hex-5-enofuranoses, 6-o-tosyl-hexofuranos-5-uloses, and 6-o-benzyl-hexofuranos-5-uloses are also described.
Buy this Article
|