Adolescence may be a tumultuous period for most and presents unique challenges for adolescents with epilepsy. Identity formation, independence, sexuality, as well as social pressures may be impacted by epilepsy. Traditionally, late adolescence is a time for ‘transfer’ of the pediatric patient to adult care. This is a critical period during which support and education for the patients with epilepsy and their caregivers is essential. The ‘transition’ should address specific topics such as understanding their epilepsy, importance of adherence to medications, reproductive issues, employment and empowerment for navigation of the healthcare system. Models for transition clinics discussed in the literature include referral ‘transfer’ letters between providers, a joint ‘hand-off’ clinic with both pediatric and adult neurologist, nurse-led clinics, and diagnosis-independent transition programs. Critical evaluation of efficacy of these programs is limited. Further investigation into what constitutes effective transition is therefore necessary.