Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
ID:
Password:
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

Agents/Distributors
 Regional Subscription Agents/Distributors
 
Trends in Inorganic Chemistry   Volumes    Volume 9 
Abstract
Coordination compounds derived from a dodecapeptide and Pb2+, Cd2+ and Zn2+. Modelling the site II from Calbindin D9K
Rosana Ferrari, Guillermo Mendoza-Díaz, Marco Tonelli, Vladimir J. Basus, Laura Gasque
Pages: 23 - 31
Number of pages: 9
Trends in Inorganic Chemistry
Volume 9 

Copyright © 2006 Research Trends. All rights reserved

ABSTRACT
 
The interaction between three divalent cations (Pb2+, Zn2+ and Cd2+) and a sequence of 12 amino-acids (DKNGDGEVSFEE) corresponding to the second binding site of Calbindin D9K, a calcium binding protein, is evaluated, as well as the conformation that this peptide can adopt due to the coordination. Equilibrium studies are performed through potentiometry and structural studies through NMR. The lead derivative shows the highest similarity to the standard conformation of the calcium-loaded site in the protein, which seems to clarify why this protein is the pathway for lead intake.
Buy this Article


 
search


E-Commerce
Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Login
Search Products
Browse in Alphabetical Order : Journals
Series/Books
Browse by Subject Classification : Journals
Series/Books

Miscellaneous
Ordering Information Ordering Information
Downloadable forms Downloadable Forms