Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

 Regional Subscription Agents/Distributors
Trends in Comparative Biochemistry & Physiology   Volumes    Volume 9 
Benzylthiocrellidone, a novel thioether with strong UV A and B absorption from the Great Barrier Reef sponge Crella spinulata, (Poecilosclerida: Crellidae)
Gerald Pattenden, Wasantha A. Wickramasinghe, Wickramasinghe M. Bandaranayake
Pages: 205 - 216
Number of pages: 12
Trends in Comparative Biochemistry & Physiology
Volume 9 

Copyright © 2002 Research Trends. All rights reserved


Benzylthiocrellidone, a novel thioether which incorporates a 5,5-dimethylcyclohexane-l,3-dione (dimedone) moiety, has been isolated from the red, encrusting marine sponge Crella spinulata collected during the reproductive season October-December 1993-1994 from the Davies and Bowden Reefs, on the Great Barrier Reef, Australia. A partial structure for the novel metabolite, which shows strong UV A and B absorption, was deduced on the basis of chemical and spectroscopic analysis and the synthesis of a degradation product. A single crystal X-ray analysis established the structure (1) for the natural product. In addition to the presence of benzylthiocrellidone, the gravid animals collected during the reproductive seasons had a strong smell of reduced sulphur compounds due to the presence of benzyl mercaptan. Dibenzyl disulphide, the oxidized product of benzyl mercaptan, was also isolated from the sponge; animals collected during other months of the year contained only a red pigment. This is the first report of a natural product containing a dimedone moiety.

Buy this Article


Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Search Products
Browse in Alphabetical Order : Journals
Browse by Subject Classification : Journals

Ordering Information Ordering Information
Downloadable forms Downloadable Forms