The collagen, particularly type I collagen, from the underutilized resources such as marine vertebrates and invertebrates was prepared and characterized. The collagen was effectively extracted from skin, bone, and fin of fish, cuttlefish and octopus outer skin, sea urchin test, and jellyfish exumbrella and mesogloea. The yields of collagen was the range of 35.0-62.9% on the dry weight basis, respectively. These under utilized resources, particularlly aquatic organisms, will have potential in supplementing the skin of land vertebrates as a source of collagen as it presently show the symptoms of bovine spongiform encephalopathy (BSE) in bovine in Japan.
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