Home | My Profile | Contact Us
Research Trends Products  |   order gateway  |   author gateway  |   editor gateway  
ID:
Password:
Register | Forgot Password

Author Resources
 Author Gateway
 Article submission guidelines

Editor Resources
 Editor/Referee Gateway

Agents/Distributors
 Regional Subscription Agents/Distributors
 
Current Topics in Biochemical Research   Volumes    Volume 10  Issue 2
Abstract
Tendon physiology, biochemistry and function: A lot of work for many players
Jaroslava Halper
Pages: 1 - 20
Number of pages: 20
Current Topics in Biochemical Research
Volume 10  Issue 2

Copyright © 2008 Research Trends. All rights reserved

ABSTRACT
 
Tendons, contrary to common thinking, are active and dynamic structures enabling the transmission of tensile forces from muscle to bone. This function depends on the proper structure of the tendon.  There are constant and reciprocal interactions between tendon structure and biochemistry on one side, and tendon mechanical function on the other.  Though type I collagen is the main structural component of tendons and thus it is the final arbitrator of biomechanical parameters, many other molecules are involved in regulation of collagen fibrils and fibers synthesis, assembly and organization. Most of these regulatory proteins are either proteoglycans (such as decorin and biglycan) or glycoproteins (such as tenascin). Others are transcription factors (e.g., scleraxis) and growth factors, most notably, TGFβ. The relationships among these components and their role in normal embryonic development, function and disease are discussed.

Buy this Article


 
search


E-Commerce
Buy this article
Buy this volume
Subscribe to this title
Shopping Cart

Quick Links
Login
Search Products
Browse in Alphabetical Order : Journals
Series/Books
Browse by Subject Classification : Journals
Series/Books

Miscellaneous
Ordering Information Ordering Information
Downloadable forms Downloadable Forms